《2026年一本密卷高考英语》

Lisa Park, 48, was suffering from gall bladder cancer, a rare but serious condition that usually only affects people in old age. “I was given a year to live,” said Park. It was a severe diagnosis, yet her prospect has recently taken an unexpected turn for the better.
Park was recently asked to join a revolutionary UK research programme known as Determine. It has been set up to target individuals with rare tumours(肿瘤) in the hope that drugs licensed for other disease could be appropriated as a new treatment.
“By definition, rare cancers are uncommon,” said one of the project’s leaders, oncologist(肿瘤学家) Matthew Krebs of Manchester University. “However, there are so many that in total they represent around 20% of all cancers diagnosed globally each year—more than any single type of cancer including lung and breast cancer.” Rare cancers’ total impact on the health service is therefore significant but there are few treatments currently available to help patients.
Determine has been set up to find if drugs that are already prescribed by doctors for more common types of cancer could benefit patients with rare cancers for which they have not been licensed. The study is led by Manchester University and involves several other leading medical centres in the UK. The ultimate aim is to match old drugs to new cancers. The crucial point is that scientists have discovered some very rare tumours possess abnormalities that could make them susceptible to treatments developed for common cancers. “We will be able to fast track the approval of any promising drugs, opening the door to treatments for patients who have been left with limited options,” said Iain Foulkes, director of research and innovation at Cancer Research UK.
The approach has already produced promising results for Park. “I know I still have a journey ahead of me but my cancer has been reduced to manageable tumours, and that has been a very welcome outcome,” said Park.
1. Why was Determine set up?
A. To develop new drugs for common cancers.
B. To treat people with lung and breast cancer.
C. To deal with a general cancer research further.
D. To target rare tumors and find new treatments.
2. How does the programme plan to do with rare cancers?
A. Develop completely new drugs.
B. Offer financial assistance for the research.
C. Use drugs available for common cancers.
D. Provide more professional care for patients.
3. What does the underlined phrase “susceptible” in Paragraph 4 mean?
A. Hard.
B. Sensitive.
C. Unaffected.
D. Different.
4. What’s the attitude of Park towards the treatment?
A. Optimistic.
B. Uncertain.
C. Indifferent.
D. Doubtful.

答案： 1.D 2.C 3.B 4.A